Abstract
Cephalotaxine (1), the major alkaloid produced by several species of Cephalotaxus (plum-yews), has been synthesized as its racemate in eight steps from 1-prolinol (4) and 3,4-methylenedioxyphenylacetyl chloride (3). Cephalotaxinone (22) and demethylcephalotaxinone (19), minor alkaloids which normally occur with cephalotaxine, have been prepared as intermediates in this synthesis.
Original language | English (US) |
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Pages (from-to) | 2503-2506 |
Number of pages | 4 |
Journal | Journal of the American Chemical Society |
Volume | 97 |
Issue number | 9 |
DOIs | |
State | Published - Apr 1 1975 |
All Science Journal Classification (ASJC) codes
- Catalysis
- General Chemistry
- Biochemistry
- Colloid and Surface Chemistry