Total synthesis of the Securinega alkaloids

Steven M. Weinreb

Research output: Contribution to journalReview articlepeer-review

65 Scopus citations


The Securinega alkaloids are a small family of plant metabolites with fascinating bridged tetracyclic structures and significant biological activity. These compounds have drawn increasing interest from synthetic chemists, resulting in a number of innovative total syntheses. This review describes the various synthetic approaches to members of the Securinega family of alkaloids published over the last four decades.

Original languageEnglish (US)
Pages (from-to)758-775
Number of pages18
JournalNatural Product Reports
Issue number6
StatePublished - Jun 2009

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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