Touch and go: Tying TonB to transport

Kathleen Postle, Robert J. Kadner

Research output: Contribution to journalShort surveypeer-review

258 Scopus citations


The TonB system of Gram-negative bacteria appears to exist for the purpose of transducing the protonmotive force energy from the cytoplasmic membrane, where it is generated, to the outer membrane, where it is needed for active transport of iron siderophores, vitamin B12 and, in pathogens, iron from host-binding proteins. In this review, we bring the reader up to date on the developments in the field since the authors each wrote reviews in this journal in 1990.

Original languageEnglish (US)
Pages (from-to)869-882
Number of pages14
JournalMolecular Microbiology
Issue number4
StatePublished - Aug 2003

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Molecular Biology


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