Towards a minimal cytoplasm

Jacqueline D. Keighron, Christine D. Keating

Research output: Chapter in Book/Report/Conference proceedingChapter

12 Scopus citations


Cytoplasm is common to all living cells and is increasingly recognized for its active role in facilitating and regulating intracellular reactions. Models for the crowded, dynamic, and compartmentalized cytoplasm should therefore be -considered for incorporation in minimal cells. This chapter begins with an -introduction to biological cytoplasm and then describes several approaches to -primitive models of the intracellular environment. Key aspects of the -cytoplasm that have been incorporated in model systems thus far include restricted -volumes, -macromolecular crowding, and colocalization or compartmentation of -biomolecular components.

Original languageEnglish (US)
Title of host publicationThe Minimal Cell
Subtitle of host publicationThe Biophysics of Cell Compartment and the Origin of Cell Functionality
PublisherSpringer Netherlands
Number of pages28
ISBN (Print)9789048199433
StatePublished - 2011

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)


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