Toxoplasma gondii Retinochoroiditis and Optic Neuritis in Acquired Immune Deficiency Syndrome: Report of a Case

Hans E. Grossniklaus; Charles S. Specht; Guy Allaire; Jacqueline A. Leavitt

doi:10.1016/S0161-6420(90)32412-0

Toxoplasma gondii Retinochoroiditis and Optic Neuritis in Acquired Immune Deficiency Syndrome: Report of a Case

Hans E. Grossniklaus, Charles S. Specht, Guy Allaire, Jacqueline A. Leavitt

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

A 29-year-old man with acquired immune deficiency syndrome (AIDS) was found to have a retinochoroiditis and optic neuritis of his left eye. Results of fundus examination showed inflammatory and hemorrhagic retinal lesions consistent with retinitis due to cytomegalovirus infection. A computed tomographic (CT) scan demonstrated enlargement of the optic nerve. The eye was enucleated and results of histopathologic examination showed retinal necrosis with underlying choroiditis and an optic neuritis. Numerous encysted Toxoplasma gondii organisms were present in the retina and tachyzoites were present in the optic nerve. To the authors' knowledge this is the second histologically documented case of Toxoplasma optic neuritis in a patient with AIDS. Ophthalmology 1990; 97:1342-1346

Original language	English (US)
Pages (from-to)	1342-1346
Number of pages	5
Journal	Ophthalmology
Volume	97
Issue number	10
DOIs	https://doi.org/10.1016/S0161-6420(90)32412-0
State	Published - 1990

All Science Journal Classification (ASJC) codes

Ophthalmology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/S0161-6420(90)32412-0

Cite this

@article{b46c05e4fe3b4c7d819fd0b03dd0c199,

title = "Toxoplasma gondii Retinochoroiditis and Optic Neuritis in Acquired Immune Deficiency Syndrome: Report of a Case",

abstract = "A 29-year-old man with acquired immune deficiency syndrome (AIDS) was found to have a retinochoroiditis and optic neuritis of his left eye. Results of fundus examination showed inflammatory and hemorrhagic retinal lesions consistent with retinitis due to cytomegalovirus infection. A computed tomographic (CT) scan demonstrated enlargement of the optic nerve. The eye was enucleated and results of histopathologic examination showed retinal necrosis with underlying choroiditis and an optic neuritis. Numerous encysted Toxoplasma gondii organisms were present in the retina and tachyzoites were present in the optic nerve. To the authors' knowledge this is the second histologically documented case of Toxoplasma optic neuritis in a patient with AIDS. Ophthalmology 1990; 97:1342-1346",

author = "Grossniklaus, {Hans E.} and Specht, {Charles S.} and Guy Allaire and Leavitt, {Jacqueline A.}",

year = "1990",

doi = "10.1016/S0161-6420(90)32412-0",

language = "English (US)",

volume = "97",

pages = "1342--1346",

journal = "Ophthalmology",

issn = "0161-6420",

publisher = "Elsevier Inc.",

number = "10",

}

TY - JOUR

T1 - Toxoplasma gondii Retinochoroiditis and Optic Neuritis in Acquired Immune Deficiency Syndrome

T2 - Report of a Case

AU - Grossniklaus, Hans E.

AU - Specht, Charles S.

AU - Allaire, Guy

AU - Leavitt, Jacqueline A.

PY - 1990

Y1 - 1990

N2 - A 29-year-old man with acquired immune deficiency syndrome (AIDS) was found to have a retinochoroiditis and optic neuritis of his left eye. Results of fundus examination showed inflammatory and hemorrhagic retinal lesions consistent with retinitis due to cytomegalovirus infection. A computed tomographic (CT) scan demonstrated enlargement of the optic nerve. The eye was enucleated and results of histopathologic examination showed retinal necrosis with underlying choroiditis and an optic neuritis. Numerous encysted Toxoplasma gondii organisms were present in the retina and tachyzoites were present in the optic nerve. To the authors' knowledge this is the second histologically documented case of Toxoplasma optic neuritis in a patient with AIDS. Ophthalmology 1990; 97:1342-1346

AB - A 29-year-old man with acquired immune deficiency syndrome (AIDS) was found to have a retinochoroiditis and optic neuritis of his left eye. Results of fundus examination showed inflammatory and hemorrhagic retinal lesions consistent with retinitis due to cytomegalovirus infection. A computed tomographic (CT) scan demonstrated enlargement of the optic nerve. The eye was enucleated and results of histopathologic examination showed retinal necrosis with underlying choroiditis and an optic neuritis. Numerous encysted Toxoplasma gondii organisms were present in the retina and tachyzoites were present in the optic nerve. To the authors' knowledge this is the second histologically documented case of Toxoplasma optic neuritis in a patient with AIDS. Ophthalmology 1990; 97:1342-1346

UR - http://www.scopus.com/inward/record.url?scp=0025009482&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025009482&partnerID=8YFLogxK

U2 - 10.1016/S0161-6420(90)32412-0

DO - 10.1016/S0161-6420(90)32412-0

M3 - Article

C2 - 2243685

AN - SCOPUS:0025009482

SN - 0161-6420

VL - 97

SP - 1342

EP - 1346

JO - Ophthalmology

JF - Ophthalmology

IS - 10

ER -

Toxoplasma gondii Retinochoroiditis and Optic Neuritis in Acquired Immune Deficiency Syndrome: Report of a Case

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this