TY - JOUR
T1 - Training status, resting metabolic rate, and cardiovascular disease risk in middle-aged men
AU - Toth, Michael J.
AU - Gardner, Andrew W.
AU - Poehlman, Eric T.
N1 - Funding Information:
From the Division of Gerontology, Department of Medicine, University of Maryland; and Baltimore Veterans Affairs Medical Center and Geriatrics Research, Education, and Clinical Center, Baltimore, MD. Submitted February 2, 1994; accepted June 2, 1994. Supported in part by the General Clinical Research Center at the University of Vermont (RR-109). M.J.T. is supported by a predoctoral training grant from the National Institute of Aging (T32-AGO0219). A.W.G. was supported by a National Research Service Award (F32-AG05564). E.T.P. is supported by a grant from the National Institute of Aging (RO1 AG-07857) and a Research Career and Development Award from the National Institute of Aging (KO4 AG-O0564). Address reprint requests to Eric T. Poehlman, PhD, Baltimore VA Medical Center, Geriatrics (18), 10 N Green St, Baltimore, MD 21201-1524. Copyright © 1995 by W.B. Saunders Company 0026-0495/95/4403-0010503.00/0
Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 1995/3
Y1 - 1995/3
N2 - We investigated differences in resting metabolic rate (RMR) and cardiovascular disease risk factors among 86 middle-aged men (36 to 59 years) classified as resistance-trained ([RT] n = 19), aerobic-trained ([AT] n = 37), or untrained ([UT], n = 30) according to habitual exercise patterns. RMR, body composition, body fat distribution, supine blood pressure, maximal aerobic capacity (Vo2max), plasma lipid levels, and fasting levels of insulin, glucose, and thyroid hormones were measured. We found that RMR, adjusted for differences in fat-free mass, showed a tendency to be greater in AT men as compared with RT men (P = .09) and was greater in AT men as compared with UT men (P < .05). No differences in RMR were noted between RT and UT men. UT men had higher values for total cholesterol, triglycerides, low-density lipoprotein cholesterol (LDL-C), and the insulin to glucose ratio and lower values for high-density lipoprotein cholesterol (HDL-C) (all P < .01) as compared with RT and AT men, whereas no differences in these variables were noted between RT and AT men. Supine diastolic blood pressure was lower in RT men as compared with both AT and UT men. Stepwise regression analysis showed that variations in body fatness accounted for the greatest variation in fasting lipid profile, blood pressure, and the insulin to glucose ratio among groups. Furthermore, statistical control for body fatness either diminished or abolished differences in cardiovascular disease risk factors among training groups. We conclude that resting energy requirements are greater in middle-aged AT men as compared with RT and UT men. Furthermore, RT and AT men displayed a comparable cardiovascular risk profile despite large differences in Vo2max. These findings suggest that attainment of low levels of body fat (via high levels of energy expenditure and/or prudent dietary practices) is an important factor associated with a favorable cardiovascular risk profile in middle-aged men.
AB - We investigated differences in resting metabolic rate (RMR) and cardiovascular disease risk factors among 86 middle-aged men (36 to 59 years) classified as resistance-trained ([RT] n = 19), aerobic-trained ([AT] n = 37), or untrained ([UT], n = 30) according to habitual exercise patterns. RMR, body composition, body fat distribution, supine blood pressure, maximal aerobic capacity (Vo2max), plasma lipid levels, and fasting levels of insulin, glucose, and thyroid hormones were measured. We found that RMR, adjusted for differences in fat-free mass, showed a tendency to be greater in AT men as compared with RT men (P = .09) and was greater in AT men as compared with UT men (P < .05). No differences in RMR were noted between RT and UT men. UT men had higher values for total cholesterol, triglycerides, low-density lipoprotein cholesterol (LDL-C), and the insulin to glucose ratio and lower values for high-density lipoprotein cholesterol (HDL-C) (all P < .01) as compared with RT and AT men, whereas no differences in these variables were noted between RT and AT men. Supine diastolic blood pressure was lower in RT men as compared with both AT and UT men. Stepwise regression analysis showed that variations in body fatness accounted for the greatest variation in fasting lipid profile, blood pressure, and the insulin to glucose ratio among groups. Furthermore, statistical control for body fatness either diminished or abolished differences in cardiovascular disease risk factors among training groups. We conclude that resting energy requirements are greater in middle-aged AT men as compared with RT and UT men. Furthermore, RT and AT men displayed a comparable cardiovascular risk profile despite large differences in Vo2max. These findings suggest that attainment of low levels of body fat (via high levels of energy expenditure and/or prudent dietary practices) is an important factor associated with a favorable cardiovascular risk profile in middle-aged men.
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U2 - 10.1016/0026-0495(95)90164-7
DO - 10.1016/0026-0495(95)90164-7
M3 - Article
C2 - 7885279
AN - SCOPUS:0028918333
SN - 0026-0495
VL - 44
SP - 340
EP - 347
JO - Metabolism
JF - Metabolism
IS - 3
ER -
