Transgenic humanized AHR mouse reveals differences between human and mouse AHR ligand selectivity

Keyphrases

• Transgenic 100%
• Aryl Hydrocarbon Receptor 100%
• Ligand Selectivity 100%
• Dioxins 20%
• Species Differences 20%
• Ligand Binding Affinity 20%
• Liver 10%
• Physiological Role 10%
• High Affinity 10%
• Inbred Strains 10%
• Toxic Effects 10%
• Receptor-ligand Binding 10%
• Halogenated 10%
• Ligand-activated Transcription Factors 10%
• Xenobiotic Metabolism 10%
• Humanized Mouse Model 10%
• Concurrent Search 10%
• Non-halogenated 10%
• Indirubin 10%
• Halogenated Polycyclic Aromatic Hydrocarbons 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Aromatic Hydrocarbon Receptor 100%
• Dioxins and Dioxin-Like Compounds 20%
• Polycyclic Aromatic Hydrocarbon 20%
• Mouse Model 10%
• Transcription Factors 10%
• Xenobiotic Metabolism 10%
• Indirubin 10%