Translating basic science to improve pharmacotherapy for nicotine dependence

Jennifer Phillips; Steven Siegel; Alexandra Shields; Freda Patterson; Thomas Gould; Andrew Strasser; Riju Ray; Angela Pinto; Janet Audrain-McGovern; Margaret Rukstalis; Kenneth Perkins; Julie Blendy; Caryn Lerman

doi:10.1080/14622200701691755

Translating basic science to improve pharmacotherapy for nicotine dependence

Jennifer Phillips, Steven Siegel, Alexandra Shields, Freda Patterson, Thomas Gould, Andrew Strasser, Riju Ray, Angela Pinto, Janet Audrain-McGovern, Margaret Rukstalis, Kenneth Perkins, Julie Blendy, Caryn Lerman

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Nicotine dependence has a complex multifactorial etiology, underscoring the value of applying a transdisciplinary research model. The important goal of treating nicotine dependence can be realized by transdisciplinary research that translates discoveries in basic neuroscience, pharmacology, genetics, and behavioral science to develop new treatment models that can be translated readily into the clinic and community. As part of this special issue highlighting work at the Transdisciplinary Tobacco Use Research Centers (TTURCs), we describe transdisciplinary research at the University of Pennsylvania TTURC aimed at elucidating the neurobiological and genetic basis of nicotine dependence, the development of novel medications, and the translation of this research to practice.

Original language	English (US)
Pages (from-to)	583-598
Number of pages	16
Journal	Nicotine and Tobacco Research
Volume	9
Issue number	SUPPL. 4
DOIs	https://doi.org/10.1080/14622200701691755
State	Published - Dec 2007

All Science Journal Classification (ASJC) codes

Public Health, Environmental and Occupational Health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/14622200701691755

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AU - Siegel, Steven

AU - Shields, Alexandra

AU - Patterson, Freda

AU - Gould, Thomas

AU - Strasser, Andrew

AU - Ray, Riju

AU - Pinto, Angela

AU - Audrain-McGovern, Janet

AU - Rukstalis, Margaret

AU - Perkins, Kenneth

AU - Blendy, Julie

AU - Lerman, Caryn

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AB - Nicotine dependence has a complex multifactorial etiology, underscoring the value of applying a transdisciplinary research model. The important goal of treating nicotine dependence can be realized by transdisciplinary research that translates discoveries in basic neuroscience, pharmacology, genetics, and behavioral science to develop new treatment models that can be translated readily into the clinic and community. As part of this special issue highlighting work at the Transdisciplinary Tobacco Use Research Centers (TTURCs), we describe transdisciplinary research at the University of Pennsylvania TTURC aimed at elucidating the neurobiological and genetic basis of nicotine dependence, the development of novel medications, and the translation of this research to practice.

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Translating basic science to improve pharmacotherapy for nicotine dependence

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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