Treatment of traumatic optic neuropathy with corticosteroids

T. C. Spoor; W. C. Hartel; D. B. Lensink; M. J. Wilkinson

doi:10.1016/S0002-9394(14)77065-5

Treatment of traumatic optic neuropathy with corticosteroids

T. C. Spoor
, W. C. Hartel
, D. B. Lensink
, M. J. Wilkinson

Research output: Contribution to journal › Article › peer-review

125 Scopus citations

Abstract

We treated 21 patients (22 eyes) with traumatic optic neuropathy by using intravenous megadose methylprednisolone (13 patients) or high-dose dexamethasone (eight patients). Of 13 patients treated with megadose methylprednisolone, 12 had improved visual function, as did seven of nine eyes treated with intravenous dexamethasone. This difference was not significant (P = .3). Initial total blindness, mechanism of injury, or time from injury to treatment did not correlate with visual improvement.

Original language	English (US)
Pages (from-to)	665-669
Number of pages	5
Journal	American Journal of Ophthalmology
Volume	110
Issue number	6
DOIs	https://doi.org/10.1016/S0002-9394(14)77065-5
State	Published - 1990

All Science Journal Classification (ASJC) codes

Ophthalmology

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10.1016/S0002-9394(14)77065-5

Cite this

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title = "Treatment of traumatic optic neuropathy with corticosteroids",

abstract = "We treated 21 patients (22 eyes) with traumatic optic neuropathy by using intravenous megadose methylprednisolone (13 patients) or high-dose dexamethasone (eight patients). Of 13 patients treated with megadose methylprednisolone, 12 had improved visual function, as did seven of nine eyes treated with intravenous dexamethasone. This difference was not significant (P = .3). Initial total blindness, mechanism of injury, or time from injury to treatment did not correlate with visual improvement.",

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AU - Spoor, T. C.

AU - Hartel, W. C.

AU - Lensink, D. B.

AU - Wilkinson, M. J.

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Y1 - 1990

N2 - We treated 21 patients (22 eyes) with traumatic optic neuropathy by using intravenous megadose methylprednisolone (13 patients) or high-dose dexamethasone (eight patients). Of 13 patients treated with megadose methylprednisolone, 12 had improved visual function, as did seven of nine eyes treated with intravenous dexamethasone. This difference was not significant (P = .3). Initial total blindness, mechanism of injury, or time from injury to treatment did not correlate with visual improvement.

AB - We treated 21 patients (22 eyes) with traumatic optic neuropathy by using intravenous megadose methylprednisolone (13 patients) or high-dose dexamethasone (eight patients). Of 13 patients treated with megadose methylprednisolone, 12 had improved visual function, as did seven of nine eyes treated with intravenous dexamethasone. This difference was not significant (P = .3). Initial total blindness, mechanism of injury, or time from injury to treatment did not correlate with visual improvement.

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U2 - 10.1016/S0002-9394(14)77065-5

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ER -

Treatment of traumatic optic neuropathy with corticosteroids

Abstract

All Science Journal Classification (ASJC) codes

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