Abstract
Inteleurkin-22 (IL-22) is a IL-10 family cytokine member and is mainly produced by innate lymphoid cells (ILCs), Th17 cells, and Th22 cells. Previous studies have indicated that IL-23 and several transcription factors, including STAT3, RORγt, and the AhR are important stimulus. Recently, there is emerging evidence that Tregs can regulate IL-22 expression. In the review, we discuss the updated advancement on Tregs function and its regulatory role on IL-22 expression.
Original language | English (US) |
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Pages (from-to) | 474-480 |
Number of pages | 7 |
Journal | International Journal of Clinical and Experimental Pathology |
Volume | 7 |
Issue number | 2 |
State | Published - 2014 |
All Science Journal Classification (ASJC) codes
- Pathology and Forensic Medicine
- Histology