Treg cells: A potential regulator for IL-22 expression?

Shuman Lin, Xuyan Yang, Dian Liang, Song Guo Zheng

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations


Inteleurkin-22 (IL-22) is a IL-10 family cytokine member and is mainly produced by innate lymphoid cells (ILCs), Th17 cells, and Th22 cells. Previous studies have indicated that IL-23 and several transcription factors, including STAT3, RORγt, and the AhR are important stimulus. Recently, there is emerging evidence that Tregs can regulate IL-22 expression. In the review, we discuss the updated advancement on Tregs function and its regulatory role on IL-22 expression.

Original languageEnglish (US)
Pages (from-to)474-480
Number of pages7
JournalInternational Journal of Clinical and Experimental Pathology
Issue number2
StatePublished - 2014

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Histology


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