TY - JOUR
T1 - Trends in prenatal prescription opioid use among Medicaid beneficiaries in Wisconsin, 2010–2019
AU - Ehrenthal, Deborah B.
AU - Wang, Yi
AU - Pac, Jessica
AU - Durrance, Christine Piette
AU - Kirby, Russell S.
AU - Berger, Lawrence M.
N1 - Publisher Copyright:
© The Author(s), under exclusive licence to Springer Nature America, Inc. 2024.
PY - 2024/8
Y1 - 2024/8
N2 - Objective: To examine changes in prenatal opioid prescription exposure following new guidelines and policies. Study design: Cohort study of all (262,284) Wisconsin Medicaid-insured live births 2010–2019. Prenatal exposures were classified as analgesic, short term, and chronic (90+ days), and medications used to treat opioid use disorder (MOUD). We describe overall and stratified temporal trends and used linear probability models with interaction terms to test their significance. Result: We found 42,437 (16.2%) infants with prenatal exposure; most (90.5%) reflected analgesic opioids. From 2010 to 2019, overall exposure declined 12.8 percentage points (95% CI = 12.1–13.1). Reductions were observed across maternal demographic groups and in both rural and urban settings, though the extent varied. There was a small reduction in chronic analgesic exposure and a concurrent increase in MOUD. Conclusion: Broad and sustained declines in prenatal prescription opioid exposure occurred over the decade, with little change in the percentage of infants chronically exposed.
AB - Objective: To examine changes in prenatal opioid prescription exposure following new guidelines and policies. Study design: Cohort study of all (262,284) Wisconsin Medicaid-insured live births 2010–2019. Prenatal exposures were classified as analgesic, short term, and chronic (90+ days), and medications used to treat opioid use disorder (MOUD). We describe overall and stratified temporal trends and used linear probability models with interaction terms to test their significance. Result: We found 42,437 (16.2%) infants with prenatal exposure; most (90.5%) reflected analgesic opioids. From 2010 to 2019, overall exposure declined 12.8 percentage points (95% CI = 12.1–13.1). Reductions were observed across maternal demographic groups and in both rural and urban settings, though the extent varied. There was a small reduction in chronic analgesic exposure and a concurrent increase in MOUD. Conclusion: Broad and sustained declines in prenatal prescription opioid exposure occurred over the decade, with little change in the percentage of infants chronically exposed.
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U2 - 10.1038/s41372-024-01954-y
DO - 10.1038/s41372-024-01954-y
M3 - Article
C2 - 38561393
AN - SCOPUS:85189146629
SN - 0743-8346
VL - 44
SP - 1111
EP - 1118
JO - Journal of Perinatology
JF - Journal of Perinatology
IS - 8
ER -