TruSPAdes: Barcode assembly of TruSeq synthetic long reads

Anton Bankevich, Pavel A. Pevzner

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

The recently introduced TruSeq synthetic long read (TSLR) technology generates long and accurate virtual reads from an assembly of barcoded pools of short reads. The TSLR method provides an attractive alternative to existing sequencing platforms that generate long but inaccurate reads. We describe the truSPAdes algorithm (http://bioinf.spbau.ru/spades) for TSLR assembly and show that it results in a dramatic improvement in the quality of metagenomics assemblies.

Original languageEnglish (US)
Pages (from-to)248-250
Number of pages3
JournalNature methods
Volume13
Issue number3
DOIs
StatePublished - Feb 25 2016

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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