Abstract
The recently introduced TruSeq synthetic long read (TSLR) technology generates long and accurate virtual reads from an assembly of barcoded pools of short reads. The TSLR method provides an attractive alternative to existing sequencing platforms that generate long but inaccurate reads. We describe the truSPAdes algorithm (http://bioinf.spbau.ru/spades) for TSLR assembly and show that it results in a dramatic improvement in the quality of metagenomics assemblies.
Original language | English (US) |
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Pages (from-to) | 248-250 |
Number of pages | 3 |
Journal | Nature methods |
Volume | 13 |
Issue number | 3 |
DOIs | |
State | Published - Feb 25 2016 |
All Science Journal Classification (ASJC) codes
- Biotechnology
- Biochemistry
- Molecular Biology
- Cell Biology