TY - JOUR
T1 - Two-Dimensional Materials in Biosensing and Healthcare
T2 - From in Vitro Diagnostics to Optogenetics and beyond
AU - Bolotsky, Adam
AU - Butler, Derrick
AU - Dong, Chengye
AU - Gerace, Katy
AU - Glavin, Nicholas R.
AU - Muratore, Christopher
AU - Robinson, Joshua A.
AU - Ebrahimi, Aida
N1 - Funding Information:
A.B., D.B., C.D., K.G., J.A.R., and A.E. would like to acknowledge The Pennsylvania State University and Materials Research Institute. D.B., J.A.R., and A.E. would also like to acknowledge the NSF:I/UCRC ATOMIC program for their support (Award No. 432-43 600U).
Publisher Copyright:
© 2019 American Chemical Society.
PY - 2019/5/10
Y1 - 2019/5/10
N2 - Since the isolation of graphene in 2004, there has been an exponentially growing number of reports on layered two-dimensional (2D) materials for applications ranging from protective coatings to biochemical sensing. Due to the exceptional, and often tunable, electrical, optical, electrochemical, and physical properties of these materials, they can serve as the active sensing element or a supporting substrate for diverse healthcare applications. In this review, we provide a survey of the recent reports on the applications of 2D materials in biosensing and other emerging healthcare areas, ranging from wearable technologies to optogenetics to neural interfacing. Specifically, this review provides (i) a holistic evaluation of relevant material properties across a wide range of 2D systems, (ii) a comparison of 2D material-based biosensors to the state-of-the-art, (iii) relevant material synthesis approaches specifically reported for healthcare applications, and (iv) the technological considerations to facilitate mass production and commercialization.
AB - Since the isolation of graphene in 2004, there has been an exponentially growing number of reports on layered two-dimensional (2D) materials for applications ranging from protective coatings to biochemical sensing. Due to the exceptional, and often tunable, electrical, optical, electrochemical, and physical properties of these materials, they can serve as the active sensing element or a supporting substrate for diverse healthcare applications. In this review, we provide a survey of the recent reports on the applications of 2D materials in biosensing and other emerging healthcare areas, ranging from wearable technologies to optogenetics to neural interfacing. Specifically, this review provides (i) a holistic evaluation of relevant material properties across a wide range of 2D systems, (ii) a comparison of 2D material-based biosensors to the state-of-the-art, (iii) relevant material synthesis approaches specifically reported for healthcare applications, and (iv) the technological considerations to facilitate mass production and commercialization.
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U2 - 10.1021/acsnano.9b03632
DO - 10.1021/acsnano.9b03632
M3 - Article
C2 - 31430131
AN - SCOPUS:85073303545
SN - 1936-0851
VL - 13
SP - 9781
EP - 9810
JO - ACS nano
JF - ACS nano
IS - 9
ER -