Two successful pregnancies after conservative treatment of endometrial cancer and assisted reproduction

M. Patrick Lowe, David Bender, Anil K. Sood, William Davis, Craig H. Syrop, Joel I. Sorosky

Research output: Contribution to journalArticlepeer-review

51 Scopus citations


Objective: To report successful pregnancies after conservative management of FIGO grade I adenocarcinoma of the endometrium. Design: Retrospective chart review Setting: University-based assisted reproduction and oncology units. Patient(s): One patient who had two separate pregnancies. Intervention(s): High-dose progestin (megestrol acetate) therapy for adenocarcinoma, followed by assisted reproduction with donor oocyte. Main Outcome Measure(s): Histologic evaluation of endometrium after megestrol acetate and at completion of childbearing, and successful pregnancies and deliveries. Result(s): The patient had complete resolution of adenocarcinoma with progestin therapy and successful delivery of two pregnancies after assisted reproduction. Conclusion(s): Conservative management of International Federation of Gynecology and Obstetrics grade I adenocarcinoma of the endometrium allows preservation of childbearing.

Original languageEnglish (US)
Pages (from-to)188-189
Number of pages2
JournalFertility and sterility
Issue number1
StatePublished - 2002

All Science Journal Classification (ASJC) codes

  • Reproductive Medicine
  • Obstetrics and Gynecology

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