Ubiquitination, proteasomes and GABAA receptors

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15 Scopus citations

Abstract

Inhibitory neurotransmission by γ-aminobutyric acid (GABA) is regulated by the number and subcellular localization of GABAA receptors in the membrane of the target neuron. A new study suggests that the ubiquitin-like protein Plic-1 stabilizes intracellular GABAA receptors and promotes their accumulation in the plasma membrane.

Original languageEnglish (US)
Pages (from-to)E232-E233
JournalNature Cell Biology
Volume3
Issue number10
DOIs
StatePublished - 2001

All Science Journal Classification (ASJC) codes

  • Cell Biology

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