Ultrasmall Enzyme Electrodes with Response Time Less than 100 Milliseconds

Joanna B. Meyerhoff, Michael A. Ewing, Andrew G. Ewing

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Glucose sensors with submicrometer tip diameter have been constructed by use of platinum-deposited flame etched carbon fiber electrodes. These electrodes have been coated with glucose oxidase and result in response times as low as 85 ms. Moreover, there is a linear relationship between sensor tip diameter and response time. Although the response is, at present, only stable over a limited number of flow injection analysis runs, it appears that sensors with tip diameter less than 100 nm might provide response times of a few milliseconds if enzyme kinetics do not become rate limiting.

Original languageEnglish (US)
Pages (from-to)308-312
Number of pages5
Issue number5
StatePublished - May 1999

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Electrochemistry


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