TY - JOUR
T1 - Unveiling the longitudinal association between short sleep duration and the incidence of obesity
T2 - The Penn State Cohort
AU - Vgontzas, A. N.
AU - Fernandez-Mendoza, J.
AU - Miksiewicz, T.
AU - Kritikou, I.
AU - Shaffer, M. L.
AU - Liao, D.
AU - Basta, M.
AU - Bixler, E. O.
N1 - Funding Information:
The work was performed at the Sleep Research & Treatment Center of the Penn State University Milton S. Hershey Medical Center and the staff (C Criley and P Cain) is especially commended for their efforts. This research was in part funded by the National Institutes of Health grants R01 51931, R01 40916 and R01 64415.
PY - 2014/6
Y1 - 2014/6
N2 - Objective: Several epidemiologic, longitudinal studies have reported that short sleep duration is a risk factor for the incidence of obesity. However, the vast majority of these studies used self-reported measures of sleep duration and did not examine the role of objective short sleep duration, subjective sleep disturbances and emotional stress. Design: Longitudinal, population-based study. Subjects: We studied a random sample of 815 non-obese adults from the Penn State Cohort in the sleep laboratory for one night using polysomnography (PSG) and followed them up for a mean of 7.5 years. Subjective and objective measures of sleep as well as emotional stress were obtained at baseline. Obesity was defined as a body mass index (BMI) ≥30 kg/ m-2. Results: The incidence of obesity was 15% and it was significantly higher in women and in individuals who reported sleep disturbances, shorter sleep duration and higher emotional stress. Significant mediating effects showed that individuals with subjective sleep disturbances who developed obesity reported the shortest sleep duration and the highest emotional stress, and that subjective sleep disturbances and emotional stress were independent predictors of incident obesity. Further analyses revealed that the association between short sleep duration, subjective sleep disturbances and emotional stress with incident obesity was stronger in young and middle-age adults. Objective short sleep duration was not associated with a significantly increased risk of incident obesity. Conclusion: Self-reported short sleep duration in non-obese individuals at risk of developing obesity is a surrogate marker of emotional stress and subjective sleep disturbances. Objective short sleep duration is not associated with a significant increased risk of incident obesity. The detection and treatment of sleep disturbances and emotional stress should become a target of our preventive strategies against obesity.
AB - Objective: Several epidemiologic, longitudinal studies have reported that short sleep duration is a risk factor for the incidence of obesity. However, the vast majority of these studies used self-reported measures of sleep duration and did not examine the role of objective short sleep duration, subjective sleep disturbances and emotional stress. Design: Longitudinal, population-based study. Subjects: We studied a random sample of 815 non-obese adults from the Penn State Cohort in the sleep laboratory for one night using polysomnography (PSG) and followed them up for a mean of 7.5 years. Subjective and objective measures of sleep as well as emotional stress were obtained at baseline. Obesity was defined as a body mass index (BMI) ≥30 kg/ m-2. Results: The incidence of obesity was 15% and it was significantly higher in women and in individuals who reported sleep disturbances, shorter sleep duration and higher emotional stress. Significant mediating effects showed that individuals with subjective sleep disturbances who developed obesity reported the shortest sleep duration and the highest emotional stress, and that subjective sleep disturbances and emotional stress were independent predictors of incident obesity. Further analyses revealed that the association between short sleep duration, subjective sleep disturbances and emotional stress with incident obesity was stronger in young and middle-age adults. Objective short sleep duration was not associated with a significantly increased risk of incident obesity. Conclusion: Self-reported short sleep duration in non-obese individuals at risk of developing obesity is a surrogate marker of emotional stress and subjective sleep disturbances. Objective short sleep duration is not associated with a significant increased risk of incident obesity. The detection and treatment of sleep disturbances and emotional stress should become a target of our preventive strategies against obesity.
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U2 - 10.1038/ijo.2013.172
DO - 10.1038/ijo.2013.172
M3 - Article
C2 - 24100421
AN - SCOPUS:84902284001
SN - 0307-0565
VL - 38
SP - 825
EP - 832
JO - International Journal of Obesity
JF - International Journal of Obesity
IS - 6
ER -