Use of astemizole in a large group practice

Timothy J. Craig, Mark Greenwald, Vanessa Kauffmann, Jill Craig

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Astemizole was released in 1988. In late 1992, a new warning label was added in response to reports of syncope and death from arrhythmia. Records of patients given new prescriptions for astemizole were reviewed to assess compliance with the warnings in a large multispecialty practice. The indication was appropriate in 89% of cases. Excessive doses were used in 4% of cases. Two percent of prescriptions were given to patients with contraindications. Only two complications were documented. Despite carrying a drug warning, astemizole continues to be used inappropriately and is a medicolegal concern. Education and drug evaluations can be used to enhance compliance and decrease the risk associated with the use of astemizole.

Original languageEnglish (US)
Pages (from-to)352-354
Number of pages3
JournalJournal of the American Osteopathic Association
Issue number6
StatePublished - 1996

All Science Journal Classification (ASJC) codes

  • Complementary and alternative medicine


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