TY - JOUR
T1 - Use of Freeze-dried Watercress for Detoxification of Carcinogens and Toxicants in Smokers
T2 - Implications of the Findings and Potential Opportunities
AU - El-Bayoumy, Karam
AU - Stoner, Gary
N1 - Publisher Copyright:
© 2022 American Association for Cancer Research
PY - 2022/3
Y1 - 2022/3
N2 - Bonorden and colleagues designed a clinical trial to test the hypothesis that daily consumption of freeze-dried watercress, a rich source of the chemopreventive agent phenethyl isothiocyanate, can enhance the detoxification of well-known tobacco and environmental carcinogens and toxicants. Initial results have validated subject compliance and a positive outcome of this study would further support the use of watercress as a whole food-based approach to cancer chemoprevention. On the basis of the design of the clinical trial and the various biological samples to be collected, we discuss potential opportunities to test future hypotheses.
AB - Bonorden and colleagues designed a clinical trial to test the hypothesis that daily consumption of freeze-dried watercress, a rich source of the chemopreventive agent phenethyl isothiocyanate, can enhance the detoxification of well-known tobacco and environmental carcinogens and toxicants. Initial results have validated subject compliance and a positive outcome of this study would further support the use of watercress as a whole food-based approach to cancer chemoprevention. On the basis of the design of the clinical trial and the various biological samples to be collected, we discuss potential opportunities to test future hypotheses.
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U2 - 10.1158/1940-6207.CAPR-21-0633
DO - 10.1158/1940-6207.CAPR-21-0633
M3 - Article
C2 - 35247882
AN - SCOPUS:85125815705
SN - 1940-6207
VL - 15
SP - 139
EP - 141
JO - Cancer Prevention Research
JF - Cancer Prevention Research
IS - 3
ER -