Use of Stang's reagent, PhI(CN)OTf, to promote Pummerer-like oxidative cyclization of 2-(phenylthio)indoles

Ken S. Feldman; Daniela Boneva Vidulova

doi:10.1016/j.tetlet.2004.04.182

Use of Stang's reagent, PhI(CN)OTf, to promote Pummerer-like oxidative cyclization of 2-(phenylthio)indoles

Ken S. Feldman
, Daniela Boneva Vidulova

Chemistry

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

Treatment of various 2-(phenylthio)indoles, bearing nucleophilic groups tethered to C(3), with PhI(CN)OTf initiated an oxidative cyclization sequence that afforded 3,3-spirocyclic 2-(phenylthio)indolenines or oxindoles in moderate yield.

Original language	English (US)
Pages (from-to)	5035-5037
Number of pages	3
Journal	Tetrahedron Letters
Volume	45
Issue number	26
DOIs	https://doi.org/10.1016/j.tetlet.2004.04.182
State	Published - Jun 21 2004

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2004.04.182

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title = "Use of Stang's reagent, PhI(CN)OTf, to promote Pummerer-like oxidative cyclization of 2-(phenylthio)indoles",

abstract = "Treatment of various 2-(phenylthio)indoles, bearing nucleophilic groups tethered to C(3), with PhI(CN)OTf initiated an oxidative cyclization sequence that afforded 3,3-spirocyclic 2-(phenylthio)indolenines or oxindoles in moderate yield.",

author = "Feldman, \{Ken S.\} and Vidulova, \{Daniela Boneva\}",

note = "Funding Information: We thank the Institute of General Medical Sciences within the National Institutes of Health (GM35727) for financial support of this work.",

year = "2004",

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doi = "10.1016/j.tetlet.2004.04.182",

language = "English (US)",

volume = "45",

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journal = "Tetrahedron Letters",

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T1 - Use of Stang's reagent, PhI(CN)OTf, to promote Pummerer-like oxidative cyclization of 2-(phenylthio)indoles

AU - Feldman, Ken S.

AU - Vidulova, Daniela Boneva

N1 - Funding Information: We thank the Institute of General Medical Sciences within the National Institutes of Health (GM35727) for financial support of this work.

PY - 2004/6/21

Y1 - 2004/6/21

N2 - Treatment of various 2-(phenylthio)indoles, bearing nucleophilic groups tethered to C(3), with PhI(CN)OTf initiated an oxidative cyclization sequence that afforded 3,3-spirocyclic 2-(phenylthio)indolenines or oxindoles in moderate yield.

AB - Treatment of various 2-(phenylthio)indoles, bearing nucleophilic groups tethered to C(3), with PhI(CN)OTf initiated an oxidative cyclization sequence that afforded 3,3-spirocyclic 2-(phenylthio)indolenines or oxindoles in moderate yield.

UR - https://www.scopus.com/pages/publications/2942633020

UR - https://www.scopus.com/pages/publications/2942633020#tab=citedBy

U2 - 10.1016/j.tetlet.2004.04.182

DO - 10.1016/j.tetlet.2004.04.182

M3 - Article

AN - SCOPUS:2942633020

SN - 0040-4039

VL - 45

SP - 5035

EP - 5037

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 26

ER -

Use of Stang's reagent, PhI(CN)OTf, to promote Pummerer-like oxidative cyclization of 2-(phenylthio)indoles

Abstract

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