Ushering in the era of regenerative surgery

Olivia P. Waldron, Jessica C. El-Mallah, Dev Lochan, Connie Wen, Mary E. Landmesser, Mohammadhossein Asgardoon, Jazzmyn Dawes, Summer N. Horchler, Kevin Schlidt, Shailaja Agrawal, Yong Wang, Dino J. Ravnic

Research output: Contribution to journalReview articlepeer-review

Abstract

Tissue loss, irrespective of etiology, often requires extensive reconstruction. in many instances, the need exceeds what current treatments and technologies modern medicine can offer. Tissue engineering has made immense strides within the past few decades due to advances in biologics, biomaterials, and manufacturing. The convergence of these three domains has created limitless potential for future surgical care. unfortunately, there still exists a disconnect on how to best implant these ‘replacement parts’ and care for the patient. it is therefore vital to develop paradigms for the integration of advanced surgical and tissue engineering technologies. This paper explores the convergence between tissue engineering and reconstructive surgery. We will describe the clinical problem of tissue loss, discuss currently available solutions, address limitations, and propose processes for integrating surgery and tissue engineering, thereby ushering in the era of regenerative surgery.

Original languageEnglish (US)
Pages (from-to)166-182
Number of pages17
JournalMinerva Surgery
Volume79
Issue number2
DOIs
StatePublished - Apr 2024

All Science Journal Classification (ASJC) codes

  • Surgery

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