Using air pollution based community clusters to explore air pollution health effects in children

Zhengmin Qian, Robert S. Chapman, Wei Hu, Fusheng Wei, Leo R. Korn, Junfeng Zhang

Research output: Contribution to journalArticlepeer-review

66 Scopus citations


To study respiratory health effects of long-term exposure to ambient air pollutant mixture, we observed 7058 school children 5-16 years of age living in the four Chinese cities of Lanzhou, Chongqing, Wuhan, and Guangzhou. These children were enrolled from elementary schools located in eight districts, one urban district and one suburban district in each of the above cities. Ambient levels of PM2.5, PM10-2.5, total suspended particles (TSP), SO2, and NOx were measured in these districts from 1993 to 1996. Based on a cluster analysis of arithmetic mean concentrations of PM2.5, PM10-2.5, (TSP-PM10), SO2, and NOx, we classified these children into four ordinal categories of exposure to ambient air pollutant mixtures. We tested for exposure-response relationships using logistic regression models, controlling for relevant covariates. We observed monotonic, positive relationships of exposure to the pollutant mixture with prevalence rates of cough with phlegm and wheeze. Other outcomes were not associated with the exposure in a monotonic exposure-response pattern. Even so, odds ratios for cough, phlegm, bronchitis, and asthma in the higher exposure district clusters were all higher than in the lowest exposure district cluster. We found evidence that exposure to the pollutant mixtures had adverse effects on children living in the four Chinese cities.

Original languageEnglish (US)
Pages (from-to)611-620
Number of pages10
JournalEnvironment international
Issue number5
StatePublished - Jul 2004

All Science Journal Classification (ASJC) codes

  • Environmental Science(all)


Dive into the research topics of 'Using air pollution based community clusters to explore air pollution health effects in children'. Together they form a unique fingerprint.

Cite this