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Utility of animal models for human embryo culture development: Domestic species

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Although the mouse is widely used as an animal model for the in vitro culture of human preimplantation embryos, arguments can be made for the validity of many domestic species as more relevant, applicable models of early human development. Here, we describe the advantages and disadvantages of domestic species as animal models to develop in vitro culture methods and conditions that successfully support human embryo development. In vitro embryo culture procedures are described and compared between species for the bovine, ovine, caprine, and porcine species.

Original languageEnglish (US)
Title of host publicationEmbryo Culture
Subtitle of host publicationMethods and Protocols
EditorsGary Smith, Jason Swain, Thomas Pool
Pages27-37
Number of pages11
DOIs
StatePublished - 2012

Publication series

NameMethods in Molecular Biology
Volume912
ISSN (Print)1064-3745

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Genetics

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