Abstract
We tested reproducibility of exhaled nitric oxide (FENO) and inter-operator handling when measured with a handheld device, NIOX MINO®. We enrolled 20 volunteers using a priori goals of acceptable reproducibility to be mean within-subject standard deviation less than 3 parts per billion (ppb) for FENO measurements less than 30 ppb, and mean coefficient of variation less than 10% for FENO measurements more than 30 ppb. Seventeen subjects with measurements less than 30 ppb displayed a mean standard deviation of 1.15, and 3 subjects with FENO more than 30 ppb had a mean coefficient of variation of 2.4%. We conclude that NIOX MINO demonstrates excellent reproducibility for all ranges of FENO.
Original language | English (US) |
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Pages (from-to) | 731-734 |
Number of pages | 4 |
Journal | Journal of Asthma |
Volume | 43 |
Issue number | 10 |
DOIs | |
State | Published - Dec 1 2006 |
All Science Journal Classification (ASJC) codes
- Pediatrics, Perinatology, and Child Health
- Immunology and Allergy
- Pulmonary and Respiratory Medicine