Variable evolutionary signatures at the heart of enhancers

Ross C. Hardison

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

What is the best way to identify regulatory DNA sequences such as enhancers, promoters, insulators and silencers? A new study shows that specific binding by a coactivator protein identifies enhancers that are invisible to common detection methods based on evolutionary constraint.

Original languageEnglish (US)
Pages (from-to)735
Number of pages1
JournalNature Genetics
Volume42
Issue number9
DOIs
StatePublished - Sep 2010

All Science Journal Classification (ASJC) codes

  • Genetics

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