Variants at the MHC Region Associate With Susceptibility to Clostridioides difficile Infection: A Genome-Wide Association Study Using Comprehensive Electronic Health Records

Keyphrases

• Electronic Health Records 100%
• Genome-wide Association Study 100%
• Clostridium Difficile Infection 100%
• MHC Region 100%
• Antibiotics 20%
• Colocalization 20%
• NOTCH4 20%
• Potential Target Genes 20%
• Meta-analysis 10%
• High Risk 10%
• Genetic Data 10%
• Mapping Method 10%
• Genome-wide Association 10%
• Healthcare Community 10%
• Fine Mapping 10%
• Tissue Type 10%
• Linear Mixed Model 10%
• Major Histocompatibility Complex 10%
• Host Immune Response 10%
• Functional Validation 10%
• Immune Defense 10%
• Clostridioides Difficile 10%
• Novel Treatments 10%
• Complex Regions 10%
• Electronic Health Record Data 10%
• Genome-wide Association Mapping 10%
• Infected Cases 10%
• Healthcare-associated 10%
• EHR Data 10%

Immunology and Microbiology

• Electronic Health Record 100%
• Genome-Wide Association Study 100%
• C4A 100%
• Upregulation 50%
• Immunity 50%
• Downregulation 50%
• Major Histocompatibility Complex 50%
• Genetic Susceptibility 50%

Medicine and Dentistry

• Infection 100%
• Electronic Health Record 100%
• Genome Wide Association Study 100%
• Meta-Analysis 10%
• Diarrhea 10%
• Upregulation 10%
• Downregulation 10%
• Immunity 10%
• Mixed Model 10%
• Major Histocompatibility Complex 10%
• Genetic Susceptibility 10%
• Tissue (Anatomy) 10%