VARICELLA-ZOSTER VIRUS RNA IN HUMAN TRIGEMINAL GANGLIA

Richard W. Hyman; Joseph R. Ecker; Richard B. Tenser

doi:10.1016/S0140-6736(83)90736-5

VARICELLA-ZOSTER VIRUS RNA IN HUMAN TRIGEMINAL GANGLIA

Richard W. Hyman
, Joseph R. Ecker
, Richard B. Tenser

Department of Medicine

Research output: Contribution to journal › Article › peer-review

145 Scopus citations

Abstract

The technique of in situ hybridisation was used to examine human trigeminal ganglia for the presence of varicella-zoster virus (VZV) RNA. The ganglia were removed from fresh cadavers of individuals without a history of current or recent herpes zoster. Of the various types of cell in the ganglia, only the neurons appeared positive for VZV RNA. 0 to 0·3% of neurons were positive for VZV RNA.

Original language	English (US)
Pages (from-to)	814-816
Number of pages	3
Journal	The Lancet
Volume	322
Issue number	8354
DOIs	https://doi.org/10.1016/S0140-6736(83)90736-5
State	Published - Oct 8 1983

All Science Journal Classification (ASJC) codes

General Medicine

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10.1016/S0140-6736(83)90736-5

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@article{c64510a6f8c64c279f9d1b67cd6168af,

title = "VARICELLA-ZOSTER VIRUS RNA IN HUMAN TRIGEMINAL GANGLIA",

abstract = "The technique of in situ hybridisation was used to examine human trigeminal ganglia for the presence of varicella-zoster virus (VZV) RNA. The ganglia were removed from fresh cadavers of individuals without a history of current or recent herpes zoster. Of the various types of cell in the ganglia, only the neurons appeared positive for VZV RNA. 0 to 0·3\% of neurons were positive for VZV RNA.",

author = "Hyman, \{Richard W.\} and Ecker, \{Joseph R.\} and Tenser, \{Richard B.\}",

note = "Funding Information: This work was supported by grants CA 16498, CA 18450, and CA 09124 from the National Cancer Institute, NIH, USPHS. Funding Information: P. F. was supported by the Max Kade Foundation.",

year = "1983",

month = oct,

day = "8",

doi = "10.1016/S0140-6736(83)90736-5",

language = "English (US)",

volume = "322",

pages = "814--816",

journal = "The Lancet",

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publisher = "Elsevier B.V.",

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T1 - VARICELLA-ZOSTER VIRUS RNA IN HUMAN TRIGEMINAL GANGLIA

AU - Hyman, Richard W.

AU - Ecker, Joseph R.

AU - Tenser, Richard B.

N1 - Funding Information: This work was supported by grants CA 16498, CA 18450, and CA 09124 from the National Cancer Institute, NIH, USPHS. Funding Information: P. F. was supported by the Max Kade Foundation.

PY - 1983/10/8

Y1 - 1983/10/8

N2 - The technique of in situ hybridisation was used to examine human trigeminal ganglia for the presence of varicella-zoster virus (VZV) RNA. The ganglia were removed from fresh cadavers of individuals without a history of current or recent herpes zoster. Of the various types of cell in the ganglia, only the neurons appeared positive for VZV RNA. 0 to 0·3% of neurons were positive for VZV RNA.

AB - The technique of in situ hybridisation was used to examine human trigeminal ganglia for the presence of varicella-zoster virus (VZV) RNA. The ganglia were removed from fresh cadavers of individuals without a history of current or recent herpes zoster. Of the various types of cell in the ganglia, only the neurons appeared positive for VZV RNA. 0 to 0·3% of neurons were positive for VZV RNA.

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UR - https://www.scopus.com/pages/publications/0020558521#tab=citedBy

U2 - 10.1016/S0140-6736(83)90736-5

DO - 10.1016/S0140-6736(83)90736-5

M3 - Article

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SN - 0140-6736

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JO - The Lancet

JF - The Lancet

IS - 8354

ER -

VARICELLA-ZOSTER VIRUS RNA IN HUMAN TRIGEMINAL GANGLIA

Abstract

All Science Journal Classification (ASJC) codes

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