TY - JOUR
T1 - Vascular Anastomoses in Growing Vessels
T2 - The Use of Absorbable Sutures
AU - Myers, John
AU - Waldhausen, John A.
AU - Pae, Walter
AU - Abt, Arthur B.
AU - Prophet, G. Allen
AU - Pierce, William S.
PY - 1982
Y1 - 1982
N2 - Primary end-to-end infrarenal aortic anastomoses were performed in 36 piglets using two synthetic absorbable suture materials: polydioxanone and coated polyglactin. Animals were killed at 1, 4, and 11 weeks and 6 months following operation. Each aorta was removed, burst-tested to 300 mm Hg, radiographed, and examined histologically. All anastomoses were patent, and no burst-test failures occurred. Stenosis occurred in 14 of 17 animals at 1 and 4 weeks, respectively. One of 5 animals exhibited stenosis at 11 weeks, and none of the 14 animals had stenosis 6 months postoperatively. Histological examination revealed fibrosis replacing areas of disrupted elastica at 6 months in both suture groups. This study suggests that absorbable suture material, in particular polydioxanone, because of its excellent handling characteristics and prolonged tensile strength retention, will be useful for the repair of vascular and cardiac anomalies where growth of the suture line is required.
AB - Primary end-to-end infrarenal aortic anastomoses were performed in 36 piglets using two synthetic absorbable suture materials: polydioxanone and coated polyglactin. Animals were killed at 1, 4, and 11 weeks and 6 months following operation. Each aorta was removed, burst-tested to 300 mm Hg, radiographed, and examined histologically. All anastomoses were patent, and no burst-test failures occurred. Stenosis occurred in 14 of 17 animals at 1 and 4 weeks, respectively. One of 5 animals exhibited stenosis at 11 weeks, and none of the 14 animals had stenosis 6 months postoperatively. Histological examination revealed fibrosis replacing areas of disrupted elastica at 6 months in both suture groups. This study suggests that absorbable suture material, in particular polydioxanone, because of its excellent handling characteristics and prolonged tensile strength retention, will be useful for the repair of vascular and cardiac anomalies where growth of the suture line is required.
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U2 - 10.1016/S0003-4975(10)62999-2
DO - 10.1016/S0003-4975(10)62999-2
M3 - Article
C2 - 6814371
AN - SCOPUS:0020374984
SN - 0003-4975
VL - 34
SP - 529
EP - 537
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
IS - 5
ER -