@article{1d848f0fdcbe4ae6910c27e980ee878b,
title = "Vilsmeier reagent, NaHSe and diclofenac acid chloride: One-pot synthesis of a novel selenoindolinone with potent anticancer activity",
abstract = "An effective and straightforward synthesis of 3-seleno functionalized indolinone (5) involving Vilsmeier reagent is presented. Likewise, a procedure to achieve lactamization of diclofenac with excellent yields by using hydrides is also ascertained. Compound 5 exhibited impressive growth inhibition in most of the cell lines in an NCI-60 panel, particularly towards resistant breast cancer cells.",
author = "Ruberte, {Ana Carolina} and Carlos Aydillo and Sharma, {Arun K.} and Carmen Sanmart{\'i}n and Daniel Plano",
note = "Funding Information: The authors thank Dr Hemant Yennawar at the X-ray diffraction facility at Penn State University for the determination of the crystal structure. C. S. and D. P. wish to express their gratitude to PIUNA (refs 2014–26 and 2018–19) and UNED–Pamplona, Fundaci{\'o}n Bancaria “La Caixa”, and “Fundaci{\'o}n Caja Navarra” for nancial support for the project. A. C. R. acknowledges the support of the Asociaci{\'o}n de Amigos de la Universidad de Navarra and Caixabank for PhD fellowship. Publisher Copyright: {\textcopyright} 2020 The Royal Society of Chemistry.",
year = "2020",
month = oct,
day = "19",
doi = "10.1039/d0ra07332f",
language = "English (US)",
volume = "10",
pages = "38404--38408",
journal = "RSC Advances",
issn = "2046-2069",
publisher = "Royal Society of Chemistry",
number = "63",
}