Abstract
An effective and straightforward synthesis of 3-seleno functionalized indolinone (5) involving Vilsmeier reagent is presented. Likewise, a procedure to achieve lactamization of diclofenac with excellent yields by using hydrides is also ascertained. Compound 5 exhibited impressive growth inhibition in most of the cell lines in an NCI-60 panel, particularly towards resistant breast cancer cells.
Original language | English (US) |
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Pages (from-to) | 38404-38408 |
Number of pages | 5 |
Journal | RSC Advances |
Volume | 10 |
Issue number | 63 |
DOIs | |
State | Published - Oct 19 2020 |
All Science Journal Classification (ASJC) codes
- General Chemistry
- General Chemical Engineering