Virtual bronchoscopy for quantitative airway analysis

A. P. Kiraly, J. M. Reinhardt, E. A. Huffman, G. McLennan, W. E. Higgins

Research output: Contribution to journalConference articlepeer-review

23 Scopus citations


We propose a new quantitative method for detailed analysis of the major airways. Using a 3D MDCT chest image as input, the method involves three major steps: (1) segmentation of the airway tree, (2) extraction of the central-axis structure of the major airways, and (3) a novel improvement on the standard full-width half-maximum approach for airway-wall delineation. The method produces measurements for all defined tree branches. These measurements include various airway diameters and cross-sectional area values. To facilitate the examination of these measurements, we also demonstrate an integrated virtual-bronchoscopic analysis system that enables flexible interrogation of the airways. Of particular note are techniques for unraveling and viewing the topography of selected airways. A large series of phantom and human tests confirm the efficacy of our methods.

Original languageEnglish (US)
Article number41
Pages (from-to)369-383
Number of pages15
JournalProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Issue numberI
StatePublished - 2005
EventMedical Imaging 2005 - Physiology, Function, and Structure from Medical Images - San Diego, CA, United States
Duration: Feb 13 2005Feb 15 2005

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging


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