Wall teichoic acid function, biosynthesis, and inhibition

Jonathan G. Swoboda; Jennifer Campbell; Timothy C. Meredith; Suzanne Walker

doi:10.1002/cbic.200900557

Wall teichoic acid function, biosynthesis, and inhibition

Jonathan G. Swoboda, Jennifer Campbell, Timothy C. Meredith, Suzanne Walker

Biochemistry & Molecular Biology

Research output: Contribution to journal › Short survey › peer-review

309 Scopus citations

Abstract

(Figure Presented) Off the wall: Wall teichoic acids (WTAs) are negatively charged glycopolymers found in dense arrays on the surface of Gram-positive bacteria. WTAs have profound effects on the physiology of Gram-positive organisms, and impact everything from cation homeostasis to antibiotic susceptibility to survival in a host. This review summarizes recent advances made toward understanding WTA function, biosynthesis and inhibition.

Original language	English (US)
Pages (from-to)	35-45
Number of pages	11
Journal	ChemBioChem
Volume	11
Issue number	1
DOIs	https://doi.org/10.1002/cbic.200900557
State	Published - Jan 4 2010

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Medicine
Molecular Biology
Organic Chemistry

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10.1002/cbic.200900557

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AB - (Figure Presented) Off the wall: Wall teichoic acids (WTAs) are negatively charged glycopolymers found in dense arrays on the surface of Gram-positive bacteria. WTAs have profound effects on the physiology of Gram-positive organisms, and impact everything from cation homeostasis to antibiotic susceptibility to survival in a host. This review summarizes recent advances made toward understanding WTA function, biosynthesis and inhibition.

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Wall teichoic acid function, biosynthesis, and inhibition

Abstract

All Science Journal Classification (ASJC) codes

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