TY - JOUR
T1 - Well-differentiated serous ovarian carcinoma presenting as a breast mass
T2 - A case report and flow cytometric dna study
AU - Frauenhoffer, Elizabeth E.
AU - Ro, Jae Y.
AU - Silva, Elvio G.
AU - El-Naggar, Adel
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1991/1
Y1 - 1991/1
N2 - Ovarian carcinoma metastatic to the breast is uncommon. We report a rare occurrence of ovarian carcinoma that initially presented as a breast mass. Complete examination revealed bilateral ovarian tumors with widespread peritoneal and abdominal disease. One of the ovarian tumors was a papillary serous tumor of low malignant potential, and the other was a well-differentiated papillary serous carcinoma. Although the neoplasm within the breast resembled serous ovarian carcinoma with psammoma bodies, the initial presentation and the presence of an apparent intraductal component created a potential for its misdiagnosis as a primary breast carcinoma. Using DNA flow cytometry, we demonstrated the relationship between the breast, lymph node, and peritoneal metastases and the serous carcinoma, thereby supporting the histologic diagnoses.
AB - Ovarian carcinoma metastatic to the breast is uncommon. We report a rare occurrence of ovarian carcinoma that initially presented as a breast mass. Complete examination revealed bilateral ovarian tumors with widespread peritoneal and abdominal disease. One of the ovarian tumors was a papillary serous tumor of low malignant potential, and the other was a well-differentiated papillary serous carcinoma. Although the neoplasm within the breast resembled serous ovarian carcinoma with psammoma bodies, the initial presentation and the presence of an apparent intraductal component created a potential for its misdiagnosis as a primary breast carcinoma. Using DNA flow cytometry, we demonstrated the relationship between the breast, lymph node, and peritoneal metastases and the serous carcinoma, thereby supporting the histologic diagnoses.
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U2 - 10.1097/00004347-199101000-00009
DO - 10.1097/00004347-199101000-00009
M3 - Article
C2 - 2007537
AN - SCOPUS:0026085347
SN - 0277-1691
VL - 10
SP - 79
EP - 87
JO - International Journal of Gynecological Pathology
JF - International Journal of Gynecological Pathology
IS - 1
ER -