TY - JOUR
T1 - Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch)
AU - Escalona, Merly
AU - Vancampen, Jake
AU - Maurer, Nicholas W.
AU - Haukness, Marina
AU - Okhovat, Mariam
AU - Harris, Robert S.
AU - Watwood, Allison
AU - Hartley, Gabrielle A.
AU - O'neill, Rachel J.
AU - Medvedev, Paul
AU - Makova, Kateryna D.
AU - Vollmers, Christopher
AU - Carbone, Lucia
AU - Green, Richard E.
N1 - Publisher Copyright:
© 2022 The American Genetic Association.
PY - 2023/1/1
Y1 - 2023/1/1
N2 - The Javan gibbon, Hylobates moloch, is an endangered gibbon species restricted to the forest remnants of western and central Java, Indonesia, and one of the rarest of the Hylobatidae family. Hylobatids consist of 4 genera (Holoock, Hylobates, Symphalangus, and Nomascus) that are characterized by different numbers of chromosomes, ranging from 38 to 52. The underlying cause of this karyotype plasticity is not entirely understood, at least in part, due to the limited availability of genomic data. Here we present the first scaffold-level assembly for H. moloch using a combination of whole-genome Illumina short reads, 10X Chromium linked reads, PacBio, and Oxford Nanopore long reads and proximity-ligation data. This Hylobates genome represents a valuable new resource for comparative genomics studies in primates.
AB - The Javan gibbon, Hylobates moloch, is an endangered gibbon species restricted to the forest remnants of western and central Java, Indonesia, and one of the rarest of the Hylobatidae family. Hylobatids consist of 4 genera (Holoock, Hylobates, Symphalangus, and Nomascus) that are characterized by different numbers of chromosomes, ranging from 38 to 52. The underlying cause of this karyotype plasticity is not entirely understood, at least in part, due to the limited availability of genomic data. Here we present the first scaffold-level assembly for H. moloch using a combination of whole-genome Illumina short reads, 10X Chromium linked reads, PacBio, and Oxford Nanopore long reads and proximity-ligation data. This Hylobates genome represents a valuable new resource for comparative genomics studies in primates.
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U2 - 10.1093/jhered/esac043
DO - 10.1093/jhered/esac043
M3 - Article
C2 - 36146896
AN - SCOPUS:85150665565
SN - 0022-1503
VL - 114
SP - 35
EP - 43
JO - Journal of Heredity
JF - Journal of Heredity
IS - 1
ER -