TY - JOUR
T1 - Wolbachia
T2 - Can we save lives with a great pandemic?
AU - LePage, Daniel
AU - Bordenstein, Seth R.
N1 - Funding Information:
The preparation of this article was supported by awards National Institutes of Health (NIH) R01 GM085163 and National Science Foundation Division of Environmental Biology (NSF DEB) 1046149 to S.R.B. and Cellular, Biochemical, and Molecular Sciences Training grant support to D.L.P. from NIH 5T32GM008554-17. We apologize in advance to our colleagues whose articles that we were unable to cite owing to space limitations.
PY - 2013/8
Y1 - 2013/8
N2 - Wolbachia pipientis is the most common bacterial infection in the animal world and wields a vast influence on invertebrate reproduction, sex determination, speciation, and behavior worldwide. These avenues of research have made seminal gains, including the latest use of Wolbachia to alter mosquito populations and a strengthened focus on using anti-. Wolbachia therapies against filarial nematode infections. This work is further bolstered by a more refined knowledge of Wolbachia biology spanning mechanisms to relevance. Here we tally the most up-to-date knowledge in the field and review the immense implications that this global infection has for the basic and applied life sciences.
AB - Wolbachia pipientis is the most common bacterial infection in the animal world and wields a vast influence on invertebrate reproduction, sex determination, speciation, and behavior worldwide. These avenues of research have made seminal gains, including the latest use of Wolbachia to alter mosquito populations and a strengthened focus on using anti-. Wolbachia therapies against filarial nematode infections. This work is further bolstered by a more refined knowledge of Wolbachia biology spanning mechanisms to relevance. Here we tally the most up-to-date knowledge in the field and review the immense implications that this global infection has for the basic and applied life sciences.
UR - http://www.scopus.com/inward/record.url?scp=84880953819&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84880953819&partnerID=8YFLogxK
U2 - 10.1016/j.pt.2013.06.003
DO - 10.1016/j.pt.2013.06.003
M3 - Review article
C2 - 23845310
AN - SCOPUS:84880953819
SN - 1471-4922
VL - 29
SP - 385
EP - 393
JO - Trends in Parasitology
JF - Trends in Parasitology
IS - 8
ER -