Wolbachia pipientis: An expanding bag of tricks to explore for disease control

Peter E. Cook; Elizabeth A. McGraw

doi:10.1016/j.pt.2010.05.006

Wolbachia pipientis: An expanding bag of tricks to explore for disease control

Peter E. Cook
, Elizabeth A. McGraw

Research output: Contribution to journal › Short survey › peer-review

38 Scopus citations

Abstract

Wolbachia pipientis are maternally inherited, endosymbiotic bacteria that are widespread among insects. Two recent studies have demonstrated that Wolbachia inhibits the ability of medically significant pathogens, including filarial nematodes, dengue virus and Plasmodium to form infections in the mosquito vector, Aedes aegypti. We highlight the added value of these traits for Wolbachia based biocontrol strategies and evaluate the evidence for the idea that the insect immune response is responsible for the pathogen inhibition.

Original language	English (US)
Pages (from-to)	373-375
Number of pages	3
Journal	Trends in Parasitology
Volume	26
Issue number	8
DOIs	https://doi.org/10.1016/j.pt.2010.05.006
State	Published - Aug 2010

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Parasitology
Infectious Diseases

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10.1016/j.pt.2010.05.006

Cite this

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title = "Wolbachia pipientis: An expanding bag of tricks to explore for disease control",

abstract = "Wolbachia pipientis are maternally inherited, endosymbiotic bacteria that are widespread among insects. Two recent studies have demonstrated that Wolbachia inhibits the ability of medically significant pathogens, including filarial nematodes, dengue virus and Plasmodium to form infections in the mosquito vector, Aedes aegypti. We highlight the added value of these traits for Wolbachia based biocontrol strategies and evaluate the evidence for the idea that the insect immune response is responsible for the pathogen inhibition.",

author = "Cook, \{Peter E.\} and McGraw, \{Elizabeth A.\}",

note = "Funding Information: The authors wish to acknowledge Scott O{\textquoteright}Neill and four anonymous reviewers for critical comment on the manuscript and the Foundation for the National Institutes of Health through the Grand Challenges in Global Health Initiative of the Bill and Melinda Gates Foundation, the National Health and Medical Research Council, Australia and the Queensland Government for grant support.",

year = "2010",

month = aug,

doi = "10.1016/j.pt.2010.05.006",

language = "English (US)",

volume = "26",

pages = "373--375",

journal = "Trends in Parasitology",

issn = "1471-4922",

publisher = "Elsevier Limited",

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}

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T1 - Wolbachia pipientis

T2 - An expanding bag of tricks to explore for disease control

AU - Cook, Peter E.

AU - McGraw, Elizabeth A.

N1 - Funding Information: The authors wish to acknowledge Scott O’Neill and four anonymous reviewers for critical comment on the manuscript and the Foundation for the National Institutes of Health through the Grand Challenges in Global Health Initiative of the Bill and Melinda Gates Foundation, the National Health and Medical Research Council, Australia and the Queensland Government for grant support.

PY - 2010/8

Y1 - 2010/8

N2 - Wolbachia pipientis are maternally inherited, endosymbiotic bacteria that are widespread among insects. Two recent studies have demonstrated that Wolbachia inhibits the ability of medically significant pathogens, including filarial nematodes, dengue virus and Plasmodium to form infections in the mosquito vector, Aedes aegypti. We highlight the added value of these traits for Wolbachia based biocontrol strategies and evaluate the evidence for the idea that the insect immune response is responsible for the pathogen inhibition.

AB - Wolbachia pipientis are maternally inherited, endosymbiotic bacteria that are widespread among insects. Two recent studies have demonstrated that Wolbachia inhibits the ability of medically significant pathogens, including filarial nematodes, dengue virus and Plasmodium to form infections in the mosquito vector, Aedes aegypti. We highlight the added value of these traits for Wolbachia based biocontrol strategies and evaluate the evidence for the idea that the insect immune response is responsible for the pathogen inhibition.

UR - https://www.scopus.com/pages/publications/77955057410

UR - https://www.scopus.com/pages/publications/77955057410#tab=citedBy

U2 - 10.1016/j.pt.2010.05.006

DO - 10.1016/j.pt.2010.05.006

M3 - Short survey

C2 - 20647151

AN - SCOPUS:77955057410

SN - 1471-4922

VL - 26

SP - 373

EP - 375

JO - Trends in Parasitology

JF - Trends in Parasitology

IS - 8

ER -

Wolbachia pipientis: An expanding bag of tricks to explore for disease control

Abstract

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