XA Cluster to remember

Gerd A. Blobel; Ross C. Hardison

doi:10.1016/j.cell.2013.07.041

XA Cluster to remember

Gerd A. Blobel, Ross C. Hardison

Research output: Contribution to journal › Short survey › peer-review

Abstract

Based on a massive transcription factor location analysis within a single cell type, in this issue Yan et al. find that the great majority of occupancies occur within dense clusters of up to 100 factors that almost invariably contain cohesins. Retention of cohesins at cluster sites during mitosis raises the possibility that they contribute to transcriptional memory during the cell cycle.

Original language	English (US)
Pages (from-to)	X718-720
Journal	Cell
Volume	154
Issue number	4
DOIs	https://doi.org/10.1016/j.cell.2013.07.041
State	Published - Aug 15 2013

All Science Journal Classification (ASJC) codes

General Biochemistry, Genetics and Molecular Biology

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10.1016/j.cell.2013.07.041

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title = "XA Cluster to remember",

abstract = "Based on a massive transcription factor location analysis within a single cell type, in this issue Yan et al. find that the great majority of occupancies occur within dense clusters of up to 100 factors that almost invariably contain cohesins. Retention of cohesins at cluster sites during mitosis raises the possibility that they contribute to transcriptional memory during the cell cycle.",

author = "Blobel, {Gerd A.} and Hardison, {Ross C.}",

note = "Funding Information: We thank Matt Deardorff and Nicole Francis for helpful suggestions. Work by the authors is supported by grants R37DK058044 and R01DK054937 (G.A.B.) and R01DK065806 and U54HG006998 (R.C.H.).",

year = "2013",

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doi = "10.1016/j.cell.2013.07.041",

language = "English (US)",

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T1 - XA Cluster to remember

AU - Blobel, Gerd A.

AU - Hardison, Ross C.

N1 - Funding Information: We thank Matt Deardorff and Nicole Francis for helpful suggestions. Work by the authors is supported by grants R37DK058044 and R01DK054937 (G.A.B.) and R01DK065806 and U54HG006998 (R.C.H.).

PY - 2013/8/15

Y1 - 2013/8/15

N2 - Based on a massive transcription factor location analysis within a single cell type, in this issue Yan et al. find that the great majority of occupancies occur within dense clusters of up to 100 factors that almost invariably contain cohesins. Retention of cohesins at cluster sites during mitosis raises the possibility that they contribute to transcriptional memory during the cell cycle.

AB - Based on a massive transcription factor location analysis within a single cell type, in this issue Yan et al. find that the great majority of occupancies occur within dense clusters of up to 100 factors that almost invariably contain cohesins. Retention of cohesins at cluster sites during mitosis raises the possibility that they contribute to transcriptional memory during the cell cycle.

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SN - 0092-8674

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SP - X718-720

JO - Cell

JF - Cell

IS - 4

ER -

XA Cluster to remember

Abstract

All Science Journal Classification (ASJC) codes

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