TY - GEN
T1 - Yarn Reinforced Gelatin Hydrogel As A New Scaffold For Tissue Engineering
AU - Rahimtoroghi, Elham
AU - Kasra, Mehran
AU - Hayes, Daniel
N1 - Publisher Copyright:
© 2019 IEEE.
PY - 2019/11
Y1 - 2019/11
N2 - We fabricated yarn reinforced hydrogel using electrospinning technique. The yarns were characterized by scanning electron microscopy (SEM). We then performed cell studies including measurements of cell viability and proliferation on the yarn reinforced hydrogel, using human adipose derived stromal/stem cells (hADSCs). hADSCs responses on the yarn reinforced hydrogel exhibited suitable cell viability and proliferation for tissue engineering applications. We also investigated the effect of yarns on the cell orientation using F-Actin staining. The results of F-Actin staining showed that the cells oriented along the yarn direction. This study introduces the yarn reinforced hydrogel as a novel scaffold with the potential to use in fibrous tissue engineering applications, such as regeneration of the annulus of the intervertebral disc.
AB - We fabricated yarn reinforced hydrogel using electrospinning technique. The yarns were characterized by scanning electron microscopy (SEM). We then performed cell studies including measurements of cell viability and proliferation on the yarn reinforced hydrogel, using human adipose derived stromal/stem cells (hADSCs). hADSCs responses on the yarn reinforced hydrogel exhibited suitable cell viability and proliferation for tissue engineering applications. We also investigated the effect of yarns on the cell orientation using F-Actin staining. The results of F-Actin staining showed that the cells oriented along the yarn direction. This study introduces the yarn reinforced hydrogel as a novel scaffold with the potential to use in fibrous tissue engineering applications, such as regeneration of the annulus of the intervertebral disc.
UR - http://www.scopus.com/inward/record.url?scp=85083372282&partnerID=8YFLogxK
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U2 - 10.1109/ICBME49163.2019.9030398
DO - 10.1109/ICBME49163.2019.9030398
M3 - Conference contribution
AN - SCOPUS:85083372282
T3 - 2019 26th National and 4th International Iranian Conference on Biomedical Engineering, ICBME 2019
SP - 66
EP - 69
BT - 2019 26th National and 4th International Iranian Conference on Biomedical Engineering, ICBME 2019
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 26th National and 4th International Iranian Conference on Biomedical Engineering, ICBME 2019
Y2 - 27 November 2019 through 28 November 2019
ER -