Chasing myocardial outcomes: perioperative myocardial infarction and cardiac troponin

Marc B. Royo, Lee A. Fleisher

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Perioperative myocardial infarction represents the most common cardiovascular complication following non-cardiac surgery, but frequently presents without the usual clinical signs and symptoms consistent with acute coronary syndrome. Given the silent nature of this event, a clinician’s reliance on risk stratification tools and cardiac specific biomarkers to assist in the identification of at-risk individuals is heightened in the perioperative setting. Although cardiac troponin elevations following non-cardiac surgery have been consistently linked to increased mortality, uncertainty remains over how to clinically intervene to prevent harm. This decision is further complicated by the increasing sensitivity of the newest generation of cardiac biomarker immunoassays. In this narrative review, the growing body of evidence surrounding cardiac troponin elevations in the perioperative setting, how the evidence has been integrated into recent clinical practice guidelines, and its implications for the detection of perioperative myocardial infarction are discussed.

Original languageEnglish (US)
Pages (from-to)227-232
Number of pages6
JournalCanadian Journal of Anesthesia
Issue number2
StatePublished - Feb 1 2016

All Science Journal Classification (ASJC) codes

  • Anesthesiology and Pain Medicine


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